ABSTRACT
Guillain–Barré syndrome is a rare manifestation of neuropsychiatric systemic lupus erythematosus (SLE). Clinical and electrophysiological features of Guillain–Barré syndrome in patients with SLE are different from those in patients without SLE. There is considerable variation in the management and prognosis. We present a patient with Guillain–Barré syndrome and SLE and review the recent knowledge on the various manifestations of neuropsychiatric SLE. Natl Med J India 2016;29:14–17
ABSTRACT
Background: Thrombosis of the cerebral venous sinuses (CSVT) is not an uncommon form of stroke. Usually affects young individuals. Aim: To compare the clinical profile of Cerebral venous thrombosis patients. Materials and methods: It was an observational study, comparing the epidemiological and etiological profile of patients with CVT during two time periods Results: This study group consisted of 130 patients, 63 patients in cohort 1 (2013/14), and 67 Patients in cohort 2 (2015-2016), were male noted in 27% and female were noted in 73% in cohort 1 (2013-14. In cohort 2 (2015-2016) male were noted in 39% and female were 61%.The data in rural were 81.5% and urban were 18.5% in cohort 1 and in cohort 2, Rural were noted in 66% and urban 34%.Common risk factors were postpartum status 31 were noted in cohort 1 and 18 were noted in cohort 2. In MRI brain Parenchymal changes cohort 1 consisted 51 and cohort 2 consisted 38. Headache was the common clinical presentation in the patients and next followed by altered sensorium. Time of onset of symptoms in the both cohorts was at 6-10 days in most of the patients, risk factor associated in both cohorts was postpartum status. Conclusion: CSVT is a multi-factorial condition with gender-related specific causes. Fifty years ago, CSVT was a mortal condition, but with the introduction of neuroimaging, the mortality rates have become minimal. CSVT is effective and economical.